Motion Correction of Positron Emission Tomography (PET) Data Using Amplitude Gating

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00843219

Enrollment

Registered

2009-02-13

Start date

2009-03-31

Completion date

2011-12-31

Last updated

2016-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Keywords

Lung, Lung Cancer, Non-small cell Lung Cancer, NSCLC, Motion Correction, PET/CT Scan, PET, Positron Emission Tomography, CT, Computed Tomography, Amplitude Gating

Brief summary

Objectives: Evaluation of an amplitude based gated Positron Emission Tomography (PET) data acquisition system for all GE Discovery Positron Emission Tomography/ Computed Tomography (PET/CT) scanners.

Detailed description

Routine PET/CT scans are taken while patients are breathing normally. The motions made by breathing can reduce the image quality of the scan. Minimizing the effects of this motion by taking the images and processing the scans differently may improve the image quality. The PET/CT Scan: If you agree to take part in this study, an elastic belt will be placed around your lower chest/upper abdomen before your routine PET/CT scan. This belt is used to track your breathing motion. This information will be used to help process the scan. Your PET/CT scan will be performed as usual. During the scan, researchers will focus on your lower chest/upper abdomen (areas that experience breathing motion). Having to focus on this area might extend the scan by up to 10 minutes. The additional scan time will not increase your radiation exposure since only PET scanning will be performed. Length of Study: Your participation on this study will be complete when your scheduled PET/CT scan is complete. This is an investigational study. The imaging focused on your lower chest/upper abdomen during the scan is investigational. Up to 26 patients will take part in this study. All will be enrolled at M. D. Anderson.

Interventions

PROCEDUREPET/CT Scan

PET/CT scan performed with elastic belt around lower chest/upper abdomen to track breathing motion.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Patients with lung or liver lesions measuring 0.5-2cm in diameter will be considered. 2. Patients that are scheduled to be imaged in the PET/CT suite at the Mays Building will only be considered.

Exclusion criteria

1. Pediatric patients (younger than 18 years) will be excluded. 2. Patients that cannot tolerate being scanned for an additional 10 minutes with arms above their head will be excluded.

Design outcomes

Primary

Measure	Time frame
Mean Difference Between Gated + Ungated PET/CT Scans	Scheduled PET/CT scans extended by 10 minutes

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026