Brain Electrophysiological Patterns in Obesity

ERP Study of Brain Electrophysiological Patterns in Obesity

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00842569

Enrollment

Registered

2009-02-12

Start date

2008-01-31

Completion date

Unknown

Last updated

2009-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

obesity, cognitive process, reward, P300, ERP, Event-related potential during oddball paradigm, brain electrophysiological patterns, externalizing factor

Brief summary

There is growing evidence of behavioural and neurobiological overlaps between obesity and drug abuse. Reduction of the amplitude of P300, a component of event-related potentials (ERP) elicited by an oddball paradigm, is an electrophysiological characteristic and a marker of vulnerability in substance abuse. We want to determine whether obesity is associated with such electrophysiological features during an auditory oddball paradigm. We postulate that obesity could be associated with electrophysiological abnormalities that could be viewed as a possible vulnerability marker for food addiction.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Eligibility

Sex/Gender

ALL

Age

20 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* The inclusion criteria for the study are men and women aged 20-60 years, BMI 18.5-24.9 kg/m2 for control subjects and BMI\>30 kg/m2 for obese subjects, stable body weight over the previous 3 months, report of sedentary or moderate physical activity

Exclusion criteria

* The

Design outcomes

Primary

Measure	Time frame
Evaluation of amplitudes and latencies of the P300 complex of Event Related Potential during an oddball paradigm, in normal-weighted and obese subjects	—

Countries

France

Outcome results