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Effects of a Specific Spice on Energy Metabolism

Effects of a Specific Spice on Energy Expenditure, Substrate Oxidation, Appetite and Energy Intake

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00841893
Enrollment
16
Registered
2009-02-11
Start date
2008-08-31
Completion date
2008-12-31
Last updated
2009-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Thermogenesis, Meal-induced thermogenesis, Energy expenditure, Fat oxidation, Carbohydrate oxidation, Bioactive ingredient, Spice

Brief summary

The objective of this study is to examine whether a specific spice is capable of affecting energy metabolism. Since chili and other spices have been shown to increase energy expenditure and in some cases also affect energy intake/appetite compared to placebo, the investigators expect that the specific spice may actually increase energy expenditure and potentially also decrease appetite - although not to a large degree.

Detailed description

Several pungent food ingredients, such as chili, and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food, since a few studies have suggested an effect of bioactive ingredients on appetite/energy intake. We expect to see some small effects on these parameters.

Interventions

DIETARY_SUPPLEMENTMustard (dijon)

The specific spice added to a brunch meal

DIETARY_SUPPLEMENTPlacebo

Placebo added to a brunch meal

Sponsors

University of Copenhagen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* male * healthy and not using medication (regularly) * normal weight * non-smoker * tolerate and like spicy food * stable body weight last two months

Exclusion criteria

* increased blood pressure * mental, metabolic and chronic diseases

Design outcomes

Primary

MeasureTime frame
Energy expenditure (resting)/Meal-induced thermogenesisNovember 2008

Secondary

MeasureTime frame
VAS-scores for different appetite parameters (incl. satiety, hunger, fullness, prospective food intake, well-being, thirst etc.)November 2008
Blood pressureNovember 2008
Heart rateNovember 2008
Substrate oxidation (fat and carbohydrate)November 2008

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026