Asthma
Conditions
Brief summary
Previously the investigators have found that adolescent elite swimmers, who have been involved in competitive swimming for only a few years, have not developed respiratory symptoms, signs of airway inflammation or airway hyperresponsiveness exept for a slight increase in airway responsiveness to eucapnic voluntary hyperpnea. In the current study, the investigators will be doing a 3-year follow-up study on the swimmers studied previously.
Detailed description
Even though studies suggest that elite sport can cause AHR and airway inflammation, more studies are needed to elucidate how and when AHR and airway inflammation develop; and there is a lack of follow-up studies. The present study will give us a chance to do a follow-up study to register changes in AHR and airway inflammation in athletes without any significant airway changes at baseline.
Interventions
None listed
Sponsors
Bispebjerg Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 19 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 15-19 years * Part of the Danish National Swimming Association's talent program for young swimmers at the baseline study * Informed consent
Exclusion criteria
* Upper respiratory tract infection in the previous 4 weeks (visits will be postponed)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Airway responsiveness to eucapnic voluntary hyperpnea and methacholine | Three years |
Secondary
| Measure | Time frame |
|---|---|
| Airway inflammation | Three years |
Countries
Denmark
Contacts
Primary ContactLars Pedersen, MD PhD
Outcome results
None listed