Total Xenoestrogen Body Burden in Relation to Mammographic Density, a Marker of Breast Cancer Rlisk

Total Xenoestrogen Body Burden in Relation to Mammographic Density, a Marker of Breast Cancer Risk

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00839696

Enrollment

270

Registered

2009-02-09

Start date

2008-07-31

Completion date

2010-04-30

Last updated

2019-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer Risk

Keywords

Breast, Estrogens, Mammography

Brief summary

Mammographic density is sensitive to estorgen exposure and constitutes a strong intermediate maker of breast cancer risk. We hypothesize that women with higher serum xenoestrogen levels will have greater mammographic density.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

55 Years to 70 Years

Healthy volunteers

Inclusion criteria

* 55-70 years of age, Post menopausal

Exclusion criteria

* If they have ever used hormone replacment therapy or have ever used Tamoxifen or Raloxifene, Diag. with breast cancer have had breast implants or have had a mastectomy/

Design outcomes

Primary

Measure	Time frame
Characterize the distribution of total xenoestrogen burden and identify important source of xenoestrogen exposure among a clinic-based sample of postmenopausal women.	1 year

Secondary

Measure	Time frame
Evaluate the association of total xenoestorgen exposure with mammographic density.	1 year

Countries

United States

Outcome results