The Effect of Music by Mozart on Energy Expenditure in Growing Preterm Infants

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00838474

Enrollment

Registered

2009-02-06

Start date

2007-10-31

Completion date

2008-07-31

Last updated

2009-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Infants

Keywords

metabolic rate, music, preterm infants, energy expenditure, NIDCA

Brief summary

Music has been consistently shown to reduce stress and increase weight gain in premature infants. The mechanism of this presumed improved metabolic efficiency is unknown. We aim to test the hypothesis that music by Mozart reduces energy expenditure in growing healthy preterm infants.

Interventions

OTHERmusic

Each infant was randomized to receive music therapy or no music over 2 consecutive days

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Eligibility

Sex/Gender

ALL

Age

No minimum to 60 Days

Healthy volunteers

Yes

Inclusion criteria

* appropriate weight for gestational age * postmenstrual age of 30-37 weeks * gavage fed * tolerating full enteral feedings without significant gastric residuals (\>5% of total feed) * no electrolyte imbalance

Exclusion criteria

* congenital anomalies * dysmorphism * intracranial hemorrhage of any grade * periventricular leukomalacia * necrotizing enterocolitis * supplemental oxygen requirements by 28 days of age or by 36 weeks of postmenstrual age and at least 1 week prior to measurement * active infection * patent ductus arteriosus * apnea of prematurity

Design outcomes

Primary

Measure	Time frame
Energy Expenditure (EE)	during measurment of EE

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026