Intrabone Cord Blood Transplantation

Pilot Study About Viability and Efficacy of Intrabone Administration of Umbilical Cord Blood for Allogeneic Stem Cell Transplantation

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00838019

Enrollment

Registered

2009-02-06

Start date

2009-02-28

Completion date

2011-02-28

Last updated

2009-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematological Malignancies

Brief summary

The purpose of this study is to evaluate the viability of intrabone administration of umbilical cord blood as allogenic transplantation for the treatment of hematologic malignancies.

Interventions

PROCEDUREIntrabone administration of umbilical cord blood

Single administration

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Hematological malignancies * Indication of allogenic transplantation * No suitable donor (related/unrelated) * No suitable cord blood unit with enough cellularity for standard transplant * Written informed consent

Exclusion criteria

* ECOG \> 2 * Co-morbidities * HIV positive serology * Pregnancy or breastfeeding * Psychiatric illness

Design outcomes

Primary

Measure	Time frame
Kinetics of hematopoietic engraftment	days 14, 21, 28 after administration

Secondary

Measure	Time frame
Dynamics and chimerism of hematological engraftment	days 14, 21, 28 after administration

Countries

Spain

Contacts

Primary ContactMontserrat Rovira, MD

mrovira@clinic.ub.es+34932275428

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026