Intraocular Pressure
Conditions
Brief summary
The purpose of this study is to determine if there is an effect on the eye pressure from extreme weight loss by bariatric procedures. The hypothesis is that excess fat in the orbit of the eye compresses on the outflow system, which causes an elevated eye pressure. This can have many consequences, including the risk for glaucoma. We hope to establish if there is an effect between eye pressure and weight.
Interventions
None listed
Sponsors
The University of Texas Health Science Center, Houston
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age ≥ 18 * Written informed consent obtained * BMI \> 40 kg/m2 without associated comorbidities or \> 35 kg/m2 with associated comorbidities. In the normal indication for routine bariatric surgery, comorbidities include hypertension, type II diabetes, venous stasis, sleep apnea, polycystic ovary syndrome, pseudotumor cerebri, nonalcoholic steatohepatitis, gastroesophageal reflux disease, coronary artery disease, degenerative joint disease, cancer, and hypercholesterolemia.
Exclusion criteria
* Current use of systemic steroids * Any systemic medication which is unstable and can affect IOP * History or evidence of glaucoma * Any ocular trauma or ocular surgery * Outside normal range of corneal thickness (500-600 microns) * Unable to follow-up for 3 years * Participating in any investigational device or medication study within 30 days of baseline
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure | Data will be recorded the same day when a patient comes to the clinic. |
Countries
United States
Outcome results
None listed