Comparison of Clomiphene Citrate and Gonadotropins in Ovulation Induction Cycles

Among Non-IVF Patients Undergoing Ovulation Induction With Clomiphene Citrate (Clomid® 50 mg), Does Administration of an Increased Dose of Clomiphene Citrate (Clomid® 100 mg) Compared With Gonadotropins, Achieve Similar Rates of Folliculogenesis?

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00835744

Acronym

cc versus FSH

Enrollment

Registered

2009-02-04

Start date

2008-08-31

Completion date

2012-03-31

Last updated

2012-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

ovulation induction, clomiphene citrate, gonadotropins

Brief summary

The purpose of the present study is to analyse prospectively if highly purified hMG compared with increased dose of clomiphene citrate has different outcomes in folliculogenesis in ovulation induction cycles.

Interventions

DRUGclomiphene citrate

ovulation induction

DRUGgonadotropins

ovulation induction

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 38 Years

Healthy volunteers

Inclusion criteria

* \< 39 years old on day of randomisation * FSH \< 12 (in the early follicular phase) * Normal ultrasound scan, i.e. presence of both ovaries, without evidence of abnormality within 6 months prior to randomisation. * Chronic oligo or anovulation (WHO 2) * BMI between 18 and 31 (both inclusive)

Exclusion criteria

* ≥ 39 years old on day of randomisation

Design outcomes

Primary

Measure	Time frame
folliculogenesis	april 2009

Secondary

Measure	Time frame
pregnancy rate	april 2009

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026