Assessment of Sleep Disturbance in Alzheimer Disease

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00831298

Enrollment

Registered

2009-01-28

Start date

2010-07-01

Completion date

2011-11-01

Last updated

2026-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer Disease

Keywords

alzheimer disease, sleep disturbance, apathy, memory loss

Brief summary

The purpose of this study is to study circadian rhythms, or daily cycles of sleep, wake, and activity. The investigators hope to learn how disturbed sleep in Alzheimer's Disease relates to changes in activity cycles, and how sleep disturbances may affect your daytime alertness. This project selects patients suffering from memory problems, or voluntary to be in our Control Group. There are three parts to this study: Sleep Diaries, Behavioral Questionnaire, and Activity Recordings

Interventions

OTHERAnalysis of sleep disturbance

Behavioral Questionnaire Sleep Recordings Genetic analysis

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* alzheimer disease * MMSE \> 20 * over 65 years old

Exclusion criteria

* new psychotropic drug treatment * patient unable to do neuropsychologic tests

Design outcomes

Primary

Measure	Time frame
assessment of apathy	at day 0, just after inclusion

Secondary

Measure	Time frame
assessment of sleep disturbance	during a week, between day 0 and day 7
determine a genetic relationship between sleep disturbance and alzheimer disease	after all genetic analyses of the study

Countries

France

Contacts

PRINCIPAL_INVESTIGATORPhilippe ROBERT

Centre Hospitalier Universitaire de Nice

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 1, 2026