Risk of Stroke in Pulmonary Embolism With a Patent Foramen Ovale (PFO)

Silent Cerebral Infarcts in Patients With Pulmonary Embolism and a Patent Foramen Ovale: a Prospective Diffusion-weighted Magnetic Resonance Imaging Study.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00831259

Acronym

ICEP

Enrollment

Registered

2009-01-28

Start date

2007-10-31

Completion date

2009-05-31

Last updated

2011-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent Foramen Ovale, Pulmonary Embolism, Silent Stroke

Keywords

stroke, PFO, embolism

Brief summary

Pulmonary embolism is associated with a small but definite risk of paradoxical embolism in patients with a patent foramen ovale (PFO). While neurologic complications are unfrequent the incidence of clinically silent brain infarction is unknown. We will assess the rate of clinically apparent and silent cerebral embolism in patients with a pulmonary embolism (PE) in relation to the presence or not of a PFO.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Pulmonary embolism, informed consent signed, no-contraindication to MRI

Exclusion criteria

* contra-indication to MRI, informed consent not obtained

Design outcomes

Primary

Measure	Time frame
Incidence of cerebral infarcts as detected by Diffusion-weighted MRI	during hospitalization

Countries

France

Outcome results