Vicryl Plus and Monocryl Plus in Breast Surgery

Pilot Study of Vicryl Plus and Monocryl Plus in Breast Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00830271

Enrollment

150

Registered

2009-01-27

Start date

2008-12-31

Completion date

2011-04-30

Last updated

2020-01-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer Surgery

Keywords

surgical site infection, wound complications, suture, antiseptic, wound closure

Brief summary

This is a randomised pilot study comparing conventional sutures (Vicryl and Monocryl) with antiseptic coated equivalents (Vicryl plus andf Monocryl plus) in elective breast surgery.

Interventions

DEVICEVicryl plus and Monocryl plus

closure of skin and subcutaneous tissues

DEVICEwound closure with Vicryl and Monocryl

wound closure skin and subcutaneous tissues

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All patients over 18 years old who attend the Cardiff and Vale NHS Trust for elective breast cancer surgery

Exclusion criteria

* patients unable to give consent or comply with follow up * patients undergoing surgery for benign disease * patients with inflammatory cancers or skin ulceration * patients having neo-adjuvant chemotherapy or radiotherapy * patients with known allergy to triclosan antiseptic * patients with immune deficiency diseases

Design outcomes

Primary

Measure	Time frame
reduction of surgical site infection	6-7 months

Secondary

Measure	Time frame
estimation time in hospital and return to work numbers of haematomas and seromas	6-9 months

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026