Impact of Three Different Gonadotrophin Regimes on Egg Donation Program

A Prospective, Randomized, Controlled Trial Comparing Three Different Gonadotrophin Regimens in Oocyte Donors: Ovarian Response and IVF Outcome

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00829075

Enrollment

Unknown

Registered

2009-01-26

Start date

2005-01-31

Completion date

2006-12-31

Last updated

2009-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Stimulation

Brief summary

Exploratory study assessing the effect of three gonadotrophin protocols on Controlled Ovarian Stimulation (COS) parameters and IVF outcome in oocyte donors undergoing GnRH analogue (long protocol). 1,028 donors were randomized in three groups: Group I (n= 346) only r-FSH, Group II (n= 333) only HP-hMG and Group III (n= 349) r-FSH plus HP-hMG. IVF outcome of 1,059 oocyte recipients was compared.

Interventions

DRUGr-FSH

DRUGHP-hMG

DRUGr-FSH plus HP-hMG

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 34 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy women 18-34 years of age * regular menstrual cycles * no family history of hereditary or chromosomal diseases * normal karyotype * BMI 18-29 Kg/m2 * negative screening for sexually transmitted diseases

Exclusion criteria

* women with PCOS were not included in this study

Design outcomes

Primary

Measure	Time frame
The aim of this study was to verify whether different gonadotrophin regimes could affect controlled ovarian stimulation (COS) parameters and IVF outcome in an egg donation program.	one year

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026