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Improving Human Ovarian Transplantation

Phase 1 Study to Improve Results of Human Ovarian Transplantation

Status
UNKNOWN
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00827476
Enrollment
100
Registered
2009-01-22
Start date
2009-01-31
Completion date
2015-01-31
Last updated
2009-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fertility Preservation

Keywords

ovary, human, transplantaion, ovarian failure

Brief summary

we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.

Detailed description

Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (\<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.

Interventions

PROCEDUREovarian transplantation

ovarian xenotransplantation or in vitro culture

Sponsors

Israel Science Foundation
CollaboratorOTHER
Hadassah Medical Organization
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
5 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* tissue previously obtained

Exclusion criteria

* no tissue available or no consent

Design outcomes

Primary

MeasureTime frame
improving folliculogenesis and oocuyte maturation after ovarian transplantation2 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026