Effect of Chili Pepper Extract on Weight and Fat Loss and Metabolism Increase

A Randomized Double-Blind Placebo-Controlled Clinical Trial of a Purified Chili Pepper Extract (CH-19 Sweet Extract) to Evaluate Its Safety and Efficacy for Weight and Fat Loss and Metabolism Change in Overweight or Obese Healthy Male and Female Adults

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00825838

Enrollment

Registered

2009-01-21

Start date

2006-04-30

Completion date

2007-03-31

Last updated

2009-01-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Overweight

Keywords

Body weight, Body composition, Resting metabolic rate and fat oxidation in men, class I obese

Brief summary

The purpose of this study is to test the safety and effectiveness of a purified extract of CH-19 Sweet, containing capsinoids.

Interventions

DIETARY_SUPPLEMENTChronic consumption of chili pepper extract

6mg chili pepper extract per day in two divided doses (before the morning meal and before the evening meal) up to 12 weeks.

DIETARY_SUPPLEMENTChronic consumption of matching placebo

0mg chili pepper extract (matching placebo) per day in two divided doses (before the morning meal and before the evening meal) up to 12 weeks.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

25 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Is overweight or obese but otherwise generally healthy who interested in losing weight * BMI of 25 to 35 kg/m2 * Waist/hip ratio of 0.9 or more for male and 0.85 for female.

Exclusion criteria

* Type 1 or 2 diabetes mellitus * cardiovascular disease (other than mild, controlled hypertension or dislidemia) * On a weight-loss program within six months

Design outcomes

Primary

Measure	Time frame
body weight and body composition	12 weeks

Secondary

Measure	Time frame
resting metabolic rate and substrate oxidation	12 weeks

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026