Flavanol-Rich Cocoa and Cerebral Blood Flow

Flavanol-Rich Cocoa, Vascular Responses and Mechanisms

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00825695

Enrollment

Registered

2009-01-21

Start date

2009-01-31

Completion date

2013-06-30

Last updated

2014-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Diabetes

Brief summary

The purpose of the study is to learn whether or not cocoa has a beneficial effect on blood flow to the brain in older subjects with diabetes mellitus or hypertension (high blood pressure). We hypothesize that cocoa, which contains flavanols (a type of polyphenol), may help to promote blood flow to the brain in older people with diabetes or hypertension.

Interventions

DIETARY_SUPPLEMENTcocoa

two servings of cocoa daily for one month

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* diabetes and/or hypertension

Exclusion criteria

* alzheimers disease, dementia, stroke, recent angina or heart attack

Design outcomes

Primary

Measure	Time frame
functional transcranial doppler measures	1 month

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026