Severe Mood Dysregulation
Conditions
Keywords
Risperidone, Severe mood dysregulation, bipolar, children
Brief summary
The purpose of this study is to investigate whether Risperidone is effective in children and adolescents with severe mood dysregulation.
Detailed description
Severe Mood Dysregulation(SMD) is a new construct in children and adolescents characterized by persistent and non episodic irritability, hyperarousal and emotional reactivity. This is an open label trial using Risperidone in children and adolescents( 7-17 years old) diagnosed with SMD. We hypothesized that Risperidone would improve externalizing symptoms as well as depressive and/or maniac symptomatology. We also consider the effect of the pharmacological intervention in the co-morbid disorders especially ADHD.
Interventions
DRUGRisperidone
0,5-4 mg/day for 8 weeks (twice a day)
Sponsors
Federal University of Rio Grande do Sul
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
7 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* Diagnose of Severe Mood Dysregulation * 7-17 years * IQ \> 70
Exclusion criteria
* Bipolar disorder * IQ\<70 * Psychosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We use as the primary outcome the subscale of irritability of the Aberrant Checklist Behavior which measures the intensity of irritability, temper tantruns and hyperarousal symptoms | 11/2010 |
Countries
Brazil
Outcome results
None listed