Lymphoma
Conditions
Keywords
Lymphoma, prognosis, morbidity
Brief summary
The purpose of this study is to establish a model which can predict the treatment outcome and the risk of treatment-related morbidity in patients with lymphoma.
Detailed description
Although the cure rate of lymphoma has been increased due to the development of newer effective drugs, a substantial portion of patients is still suffered from relapse. Furthermore, the treatment-related morbidity is another factor which can make the treatment outcome worse in patients with lymphoma, especially elderly patients. Thus, this study is going to assess following factors which amy probably affect the treatment outcome and the risk of treatment-related morbidity. 1. Biologic factors associated with the aggressiveness of lymphoma * molecular markers in serum, cytogenetic markers 2. Factors associated with the risk of treatment-related morbidity * comorbidity, nutrition status, performance status, quality of life at diagnosis
Interventions
DRUGChemotherapy with or without radiotherapy
Treatment regimen will be determined by the sub-type of lymphoma
Sponsors
Samsung Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients who were diagnosed as lymphoma * Over 15 years old * Patients who agreed the enrollment of study * Informed consent for sampling
Exclusion criteria
* Patients who do not want to join the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| all cause mortality | 5 years |
Secondary
| Measure | Time frame |
|---|---|
| Treatment response | after completion of primary therapy |
| Rate of occurrence of toxicity | 2 years from the start of the 1st therapy |
| Treatment-related morbidity | within 60 days from the previous therapy |
Countries
South Korea
Outcome results
None listed