Improvement of Language Disturbances After Stroke by Intensive Training and Electrical Brain Stimulation

Improvement of Aphasia After Stroke by Intensive Training and Transcranial Direct Current Stimulation

Status

UNKNOWN

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00822068

Enrollment

Registered

2009-01-14

Start date

2009-01-31

Completion date

2009-12-31

Last updated

2009-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia, Stroke

Keywords

stroke, aphasia, rehabilitation, transcranial direct current stimulation, intensive training, chronic aphasia after stroke

Brief summary

The study aims to identify if intensive language training, consisting mainly of computer-based object naming, together with electrical brain stimulation, will lead to an improvement of language functions in patients that suffer from language disturbances after a stroke.

Interventions

DEVICEanodal tDCS

anodal transcranial direct current stimulation

DEVICEcathodal tDCS

cathodal transcranial direct current stimulation

DEVICEsham stimulation

sham stimulation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* chronic stroke (\> 1 year after event) * aphasia due to stroke with naming impairment * German as first language * first-ever stroke

Exclusion criteria

* more than 1 stroke * progressive stroke * history of severe alcohol or drug abuse, psychiatric illnessess like severe depression, poor motivational capacity * dementia * contraindications for Magnetic Resonance Imaging

Design outcomes

Primary

Measure	Time frame
Number of words correctly named after training plus tDCS	1 year

Secondary

Measure	Time frame
Communicative-Activity-Log & Stroke-and-Aphasia-Quality-of-Life-Scale	1 year

Countries

Germany

Contacts

Primary ContactAgnes Floel, MD

floeel@uni-muenster.de0049 251 83

Backup ContactCaterina Breitenstein, PhD

breitens@uni-muenster.de0049 251 83

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 29, 2026