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Left Versus Right Transradial Approach for Percutaneous Coronary Procedures

Transradial Approach [LEft vs Right] aNd Procedural Times During Percutaneous Coronary Procedures: TALENT Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00821106
Acronym
TALENT
Enrollment
1540
Registered
2009-01-13
Start date
2009-01-31
Completion date
2009-12-31
Last updated
2010-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angioplasty, Transluminal, Percutaneous Coronary, Coronary Angiography

Keywords

Coronary angiography, percutaneous coronary intervention, Transradial approach

Brief summary

Transradial approach of cardiac catheterization is a common alternative to transfemoral access for diagnostic coronary angiography and percutaneous coronary interventions (PCI). The transradial approach reduces access site bleeding complications and the procedural discomfort of the patients. Transradial procedures may be performed by cannulation of the right or left radial artery and at present, the choice of the right or left radial artery depends largely on the operator' s preference. The aim of this study is to evaluate safety and efficacy of transradial approach comparing the right radial versus the left radial approach in coronary diagnostic and interventional procedures. The investigators will enroll consecutively for 12 months all patients who undergo to diagnostic or interventional procedures through trans radial approach in two Italian centers (Casilino Policlinic, Catholic University-Rome). Primary end point of the study is the fluoroscopy time and the radiation dose adsorbed by the patients. Secondary end-points are: contrast amount, time to obtain the first angiography, procedural shift rate, number of catheters employed, major complications. The investigators pre-specified a sub-study in patients older than 75 years old with the same end-points.

Interventions

PROCEDURERight radial

diagnostic or interventional procedures performed through right transradial approach

PROCEDUREleft radial

diagnostic or interventional procedures performed through left transradial approach

Sponsors

Policlinico Casilino ASL RMB
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients who undergo to diagnostic or interventional procedures

Exclusion criteria

* Previous coronary artery by-pass * Acute myocardial infarction with ST segment elevation myocardial infarction * Cardiogenic shock * Ischemic Allen Test

Design outcomes

Primary

MeasureTime frame
Primary end point of the study is the fluoroscopy time of the procedure and the radiation dose adsorbed by the patients7 days

Secondary

MeasureTime frame
Contrast amount, time to obtain the first angiography, procedural shift rate, number of catheters employed, major complications.7 days

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026