Asthma
Conditions
Keywords
Asthma, Asthmatic subjects, Exercise training, Constant load, Alternate load
Brief summary
The aim of the study is to compare two methods of exercise training: alternate load versus constant load realized at moderate or high intensities, in order to define the interests and the limits of each one of these two methods. The finality is to make possible to the expert to choose what exercise training induces the best results quickly and to make its choice according to the therapeutic objectives which it lays down.We also evaluate the effects of these exercises training on the vagal response and the bronchial tone of the asthmatics. From a clinical point of view, a close attention will be paid to the effects of these exercises training on the control of asthma and the quality of life of the subjects
Interventions
OTHERExercise training
Comparison of two methods of exercise training: alternate load versus constant load realized at moderate or high intensities
Sponsors
University Hospital, Strasbourg, France
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* 18 to 45 years old * mild to moderate persistent asthma (GINA classification) * stabilized asthma * physical activity level between 5 and 11 (Baecke and coll, 1982) * no contra-indication for physical training
Exclusion criteria
* cardiovascular pathology * metabolic pathology * traumatic pathology * BMI≥30 * tobacco * diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximal oxygen consumption (VO2max) | At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training |
| Maximal power output (Pmax) | At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training |
Secondary
| Measure | Time frame |
|---|---|
| Exhaled NO (eNO) | At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training |
| Heart rate variability | At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training |
| Force Expiratory Volume in one second (FEV1) | At T-1 = eight weeks before training - At T0 = beginning of training - At T1 = eight weeks after training |
Countries
France
Outcome results
None listed