Differential Effects of Milk Proteins on Postprandial Lipemia in Response to a Fat-Rich Meal in Type 2 Diabetes

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00819975

Enrollment

Registered

2009-01-09

Start date

Unknown

Completion date

2008-05-31

Last updated

2009-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postprandial Lipemia, Type 2 Diabetes

Keywords

Casein, Whey, postprandial, Triglyceride, Free fatty acids, Retinyl palmitate, Incretins, Type 2 Diabetes

Brief summary

Enhanced and prolonged postprandial triglyceride responses involve increased cardiovascular risk in type 2 diabetes. It has been demonstrated that dietary fat and carbohydrates profoundly influence postprandial hypertriglyceridemia in type 2 diabetes, whereas little information exists about the effect of proteins. The purpose of this study is to compare the effects of the milk proteins casein, Whey Isolate, Whey Hydrolysate, and Alphalact-Albumin on postprandial lipid and incretin responses to a high-fat meal in type 2 diabetes.

Interventions

DIETARY_SUPPLEMENTCasein

DIETARY_SUPPLEMENTWhey Isolate

DIETARY_SUPPLEMENTWhey Hydrolysate

DIETARY_SUPPLEMENTAlphalact-Albumin

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

40 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Type 2 Diabetes

Exclusion criteria

* Liver-, Kidney- and/or Heart Disease * Serious Hypertension (160/110 mmHg)

Design outcomes

Primary

Measure	Time frame
Triglyceride levels	0h- 2h- 4h- 6h- 7h- 8h postprandial

Secondary

Measure	Time frame
Incretin levels	0h- 0.5h- 1h- 2h- 4h- 6h- 8h postprandial

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026