Role of Skin Tests for the Diagnosis of Immediate Hypersensitivity Reactions Due to Iodinated Contrast Media

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00819494

Enrollment

Registered

2009-01-09

Start date

2008-11-30

Completion date

2009-03-31

Last updated

2010-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypersensitivity

Keywords

Contrast media skin test, Skin test, hypersensitivity, contrast media

Brief summary

The purpose of this trial is to study the diagnostic role of skin test in immediate reactions to iodinated radiocontrast media.

Interventions

PROCEDURESkin tests with radiocontrast media

Skin prick tests and intradermal test will be performed in patients with a history of immediate reactions to iodinated radiocontrast media

Study design

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

15 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients with history of immediate hypersensitivity reactions to iodinated contrast media 2. 15-70 years of age

Exclusion criteria

1. On antihistamine/ cannot discontinue antihistamine before the test 2. Having asthma exacerbation 3. Being pregnant 4. Suffering from severe systemic disease/ in bad health

Design outcomes

Primary

Measure	Time frame
Percentages of positive wheal and flare responses from skin test in patients with a history of immediate reactions to radiocontrast media	5 months

Secondary

Measure	Time frame
Blood in vitro test from patients with a history of immediate reactions to radiocontrast media	5 months

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026