Contact Lenses Dryness
Conditions
Keywords
Contact lenses, Loteprednol, Effect on CL dryness
Brief summary
Study of the effects of Loteprednol on CL dryness
Interventions
DRUGLoteprednol
Anti-inflammatory
OTHERRewetter
Sponsors
Bausch & Lomb Incorporated
Hom, Milton M., OD, FAAO
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Between the ages of 18 and over inclusive. 2. Males or females 3. Any race or ethnic background 4. CL history- experienced intolerance and either switched solutions or lenses without satisfactory relief. 5. Patient is in generally good & stable overall health. 6. Patient likely to comply with study guidelines & study visits. 7. Informed consent signed. 8. OSDI score 18 or higher while wearing lenses 9. Unsatisfactory wearing time with contact lenses
Exclusion criteria
1. Corneal refractive surgery within 6 months of this study. 2. Contact lens use on day of examination. 3. Corneal ectasia. 4. Current use of Restasis 5. Intra-ocular surgery within 6 months or ocular laser surgery within 6 months. 6. Pregnant or lactating women. 7. Ocular pathology (includes glaucoma and cataract) which could impact results and/or place patient at risk.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wearing time | 28 days |
Secondary
| Measure | Time frame |
|---|---|
| OSDI | 28 days |
Countries
United States
Outcome results
None listed