Central Serous Chorioretinopathy
Conditions
Keywords
CSR, Helicobacter pylori
Brief summary
Etiology of ICSCR is not known however recent studies regard the role of immunologic and infectious processes in the pathogenesis of ICSCR.one of these hypothesis is the role of helicobacter pylori in the pathogenesis of ICSCR so perhaps treatment of h pylori have positive effect on the remission of ICSCR.
Detailed description
we will choose 50 cases of patients with ICSCR who are infected with h.pylori.25 cases will receive anti h.pylori regiment and 25 cases as controls will receive no medication.then we will compare the time of submacular fluid resorption and macular thickness and visual acuity among these two groups.
Interventions
DRUGomeprazole, Amoxicillin, metronidazole
we will evaluate the effect of medication(anti h.pylori) on the remission of ICSCR
Sponsors
Tabriz University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
28 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* the persons who are infected with helicobacter pylori and have ICSCR
Exclusion criteria
* history of previous eye surgery ,to have indication of laser therapy,corticosteroid therapy,pregnancy,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subretinal fluid level | — |
Secondary
| Measure | Time frame |
|---|---|
| time of sub macular fluid absorption | — |
Countries
Iran
Outcome results
None listed