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A Prospective Randomized Study of Medial Patellofemoral Ligament (MPFL) Reconstruction

A Prospective Randomized Study of Medial Patellofemoral Ligament Reconstruction Compared With Medial Reefing

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00816647
Enrollment
50
Registered
2009-01-01
Start date
2008-12-31
Completion date
2011-06-30
Last updated
2011-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patella-Dislocation, Patellar Instability, Patellofemoral Osteoarthritis

Keywords

Patella, Dislocation, Knee, Medial Patellofemoral Ligament

Brief summary

The operative management of chronic patellar instability has been controversial. Medial patellofemoral ligament reconstruction has gained success recently and might be superior to other soft-tissue procedures. The objective of this prospective study was to compare the clinical outcome after medial patellofemoral ligament reconstruction compared with medial reefing for chronic patellar instability.

Detailed description

Many of the previous studies on medial patellofemoral ligament (MPFL) reconstruction for patellar instability have been difficult to interpret, either because the study setting has included both first-time and recurrent dislocations, or because a lack of control group. Moreover, several studies have enrolled patients with a wide age range, and the majority of the studies have employed retrospective and nonrandomized study designs. Therefore the investigators designed a prospective, randomized study with the primary goal to compare the outcome after MPFL reconstruction with medial reefing for chronic patellar instability. The distance between tibial tubercle and trochlear groove is measured on MRI and corrected if it exceeds 17mm. Primary outcome measure is the occurrence of recurrent objective and subjective patellar instability. The second goal is to evaluate the development of articular cartilage lesions within the patellofemoral joint, and assess clinical scores.

Interventions

PROCEDUREPatellofemoral stabilizing surgery

Comparison of surgical techniques

Sponsors

Tampere University Hospital
CollaboratorOTHER
Finnish Defense Forces
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Chronic patellar instability (more than 2 dislocations) * Minimum 6 months nonoperative treatment

Exclusion criteria

* Severe PF OA * Acute patellar dislocation

Design outcomes

Primary

MeasureTime frame
Recurrent patellar instability2 years

Secondary

MeasureTime frame
Patellofemoral osteoarthrosis progression.2 years

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026