Pleth Variability Index and Fluid Management During Surgery

Is Pleth Variability Index Able to Guide Fluid Management During Surgery?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00816153

Enrollment

Registered

2008-12-31

Start date

2008-03-31

Completion date

2008-08-31

Last updated

2008-12-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid Management

Keywords

Pleth variability Index, Fluid management, Fluid management during surgery

Brief summary

Pleth Variability Index (PVI) seems to be an ideal parameter to guide fluid management: dynamic parameter and non-invasive. PVI could guide fluid management during surgery and optimization of the plethysmographic-derived parameter could improve hemodynamics of the patients.

Interventions

OTHERPVI-guided fluid management

Peroperative comparison of standard care with PVI-guided fluid management (optimization of the PVI value with fluid loading)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Major abdominal surgery

Exclusion criteria

* Refusal or inability to understand the protocol * Arrythmia * \<18 years * Contraindication to normal mechanical ventilation

Design outcomes

Primary

Measure	Time frame
Hemodynamics and derived-parameters	The first 48 h

Secondary

Measure	Time frame
All causes of morbi-mortality	—

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026