Diabetes Complications, Inspiratory Muscle Weakness
Conditions
Keywords
inspiratory muscle weakness, autonomic modulation, diabetes mellitus, heart rate variability, functional capacity
Brief summary
The purpose of the study is to determine if inspiratory muscle training improves inspiratory muscle strength of type 2 diabetes mellitus patients with inspiratory muscle weakness.
Detailed description
In congestive heart failure patients, inspiratory muscle weakness can be reversed by developing diaphragmatic hypertrophy through inspiratory muscle training, improving functional capacity and quality of life. In type 2 diabetes mellitus patients the frequency of inspiratory muscle weakness is unknown, as well as the response to inspiratory muscle training. For this reason, the present study evaluated the inspiratory muscle strength in type 2 diabetes mellitus patients and the effect of inspiratory muscle training on inspiratory muscle strength, pulmonary function, functional capacity and autonomic modulation assessed through heart rate variability.
Interventions
BEHAVIORALInspiratory muscle training
For Inspiratory muscle training (IMT)patients carried out the IMT on a daily basis for eight weeks, with duration of 30 minutes and intensity corresponding to 30% of resting PImax, with a linear pressure resistance device (Threshold®). Weekly maximum inspiratory pressure (PImax) evaluations and workload adjustments were performed. Inspiratory load was adjusted on a weekly basis to maintain 30% of the subject's PImax. Training sessions were carried out at home for both groups and supervised once a week at the hospital.
BEHAVIORALInpiratory muscle training placebo
Inspiratory muscle training was carried out on the same basis as in the intervention group but with no inspiratory load.
Sponsors
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Hospital de Clinicas de Porto Alegre
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* diabetes melittus * sedentary * inspiratory muscle weakness with PImax \< 70% of the predicted
Exclusion criteria
* mass index \> 33 kg/m2 * exercise-induced asthma history * infectious disease * osteoarticular disease * regular alcohol or tobacco consumption in the past 6 months * cardiac disease * pulmonary disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum inspiratory pressure | 8 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Peak exercise oxigen consumption | 8 weeks |
| pulmonary function | 8 weeks |
| autonomic modulation assessed by heart rate variability | 8 weeks |
Countries
Brazil
Outcome results
None listed