Glycosaminoglycans During Septic Shock - a Temporal Study

GAGS - Glykosaminoglykaner Vid Sepsis

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00814112

Acronym

GAGS

Enrollment

Registered

2008-12-23

Start date

2008-11-30

Completion date

2010-11-30

Last updated

2024-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic Shock

Brief summary

We have previously shown that the plasma level of glycosaminoglycans (GAG) in septic shock patients are elevated compared to controls. The purpose of this study is to investigate the temporal dynamic of the blood level of GAG in ten septic shock patients. In addition, to assess the kinetics of GAG during septic shock we examine the liver function by galactose elimination capacity as well as excreted urinary GAG.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Yes

Inclusion criteria

* 2 out of 4 SIRS criteria, where the circulatory criteria must be fulfilled * Clinical sepsis is suspected * Informed consent from relative * Study subject must be over 18 years old

Exclusion criteria

* Pregnancy * \>24h post sepsis diagnosis * Ongoing oral or intravenous cortisone treatment for more than one month. * Malignancy with metastasis

Countries

Sweden

Outcome results