Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using Multi-exponential T2 Components

Investigation Into the Differentiation of Tumour and Healthy Brain Tissue Using a Specialized MRI Technique Called Multiexponential T2 Component Analysis

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00813787

Enrollment

Registered

2008-12-23

Start date

2009-02-28

Completion date

2015-04-30

Last updated

2014-10-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioma

Keywords

Magnetic Resonance Imaging, Glioma

Brief summary

The purpose of this study is to see if a specialized imaging technique using MRI called multi-exponential T2 component analysis can reliably differentiate between normal brain and brain tumour.

Detailed description

Existing methods of contouring tumours for radiation therapy involve manual interpretations of qualitative diagnostic images. These methods, being qualitative, do not offer a consistent and reproducible platform for contouring, making it difficult to evaluate the effects of contouring choices on treatment outcome. T2 component analysis in MRI has the potential to offer a quantitive basis for identifying tumor tissue- this potential is investigated in this pilot study.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Eighteen years of age or older * Clinical subjects must have not yet begun radiation therapy * Must have signed our study-specific consent form

Exclusion criteria

Design outcomes

Primary

Measure	Time frame
T2 characteristics of glioma tissue versus normal	Before radiotherapy treatment begins

Countries

Canada

Contacts

Primary ContactKeith Wachowicz, PhD

keithwac@cancerboard.ab.ca(780) 989-4334

Outcome results