Colonic Neoplasms
Conditions
Keywords
Colonic Neoplasms, Aerobic Exercise, Weight Lifting, Body Composition
Brief summary
Recent studies have suggested that individuals diagnosed with colon cancer who are inactive and/or overweight, may have poorer survival outcomes. Exercise training has been shown to improve fitness and body composition in other cancer survivor groups. The investigators hypothesize that an exercise training program will be a safe, feasible, and effective intervention to improve the fitness and body composition of a group of colon cancer survivors.
Interventions
BEHAVIORALExercise Training
The exercise group will perform supervised stationary cycle ergometer exercise 3 times per week for 12 weeks and be progressed from 15 to 45 minutes and 60% to 110% of the power output obtained at V02peak. Resistance training will be completed twice per week and will include exercises for all major muscle groups. The training will progress from 60% to 80% of 1RM over the course of the intervention.
OTHERUsual Care
Usual Care
Sponsors
AHS Cancer Control Alberta
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Histologically confirmed Stage II or III colon cancer diagnosis * Less than or equal to 1 year since the completion of all adjuvant treatment * Negative Physical Activity Readiness Questionnaire (PAR-Q) or completed Physical Activity Readiness Medical Examination (PARmed-X) form * 18 years of age or older * Ability to understand and provide written informed consent in English * Willingness to be randomized * Willingness to complete outcome measures at each assessment time point * Available for the duration of study intervention period * Able to travel to our fitness centre 3/week for the study period
Exclusion criteria
* Any absolute contraindication to to exercise testing or training * Evidence of active disease (metastatic, recurrent, or unresectable colon cancer) * Any uncontrolled medical condition or psychiatric illness that would prevent completion of the exercise program or interfere with the study assessments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety (Monitoring for Adverse Events) | 12 Weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change in Aerobic Capacity | Baseline and 12 Weeks |
| Change in body composition | Baseline and 12 Weeks |
| Feasibility (Adherence to the exercise training program) | 12 weeks |
Countries
Canada
Outcome results
None listed