Diabetes
Conditions
Keywords
diabetes, genetics, oral glucose tolerance testing, family history of diabetes, gestational diabetes
Brief summary
* This study is in the area of Type 2 diabetes and genetics * Healthy Volunteers and those with mild type 2 diabetes may be eligible to participate * This study is searching for genes that may affect the body's processing/digestion of glucose/sugar
Detailed description
This study is looking at the genetic influences of type 2 diabetes. It also is investigating the various gastric hormones including but not limited to: insulin, C-peptide, GIP, GLP, & Xenin.
Interventions
None listed
Sponsors
University of Chicago
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Washington University School of Medicine
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* ages 18-65 * non-diabetic * diabetes controlled with diet or with pills * no family history of diabetes * family history of type 2 diabetes * personal history of gestational diabetes
Exclusion criteria
* \< 18 or \> 65 years of age * medications that affect glucose (sugar) levels * kidney disease * liver disease * heart/cardiovascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genes affecting the development of Type 2 diabetes will be identified | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| Any differences between genetic groups in the metabolism of glucose/sugar will be studied to the extent that the data allow | 1 year |
Outcome results
None listed