Gulf War Illness, Persian Gulf War Syndrome
Conditions
Keywords
CNDP1, carnosine dipeptidase 1, Persian Gulf War, Gulf War Syndrome, GWI, Gulf War Illness, Exercise, Chronic Fatigue, Fibromyalgia, Veterans, Irritable Bowel Syndrome, Migraine headaches, Neuropathy, Multiple Chemical Sensitivity
Brief summary
Determine if: * genetic differences of CNDP1 gene * the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents * psychometric * other variables can differentiate between veterans of the 1990-1991 Persian Gulf War who have autonomic, neurological and other symptoms and those without these complaints.
Interventions
None listed
Sponsors
U.S. Army Medical Research and Development Command
Georgetown University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Evidence of military enlistment between August 1, 1990 and July 31, 1991, and deployment for 30 consecutive days to: * Persian Gulf waters and adjacent land areas * Other global locations * U.S. only * Status prior to 1990 and 1991: * Active duty * National Guard * Reserves
Exclusion criteria
* Current active duty military personnel * Any one who was not active duty military personnel between August 1, 1990 and July 31, 1991 * HIV/AIDS; pregnancy or lactation; potential hepatitis; drug addiction; chronic inflammatory, infectious, or autoimmune medical illnesses not associated with GWI; incarceration; dementia, other cognitive limitation; or reliance on a care-giver in order to respond to the questionnaires and other study tests. Amputations of one or both hands and forearms will be permitted but hand grip tests will not be tested
Countries
United States
Outcome results
None listed