Frozen Embryo Transfer (FET) in Natural Cycles or in Natural Cycles Controlled by Human Chorionic Gonadotropin (hCG) Administration

Cryopreserved-Thawed Embryo Transfer in Natural Cycle or in Natural Cycles Controlled by External Administration of hCG: a Prospective Randomized Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00809107

Acronym

FRET

Enrollment

150

Registered

2008-12-17

Start date

2006-10-31

Completion date

2009-01-31

Last updated

2009-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

natural cycle, FET, spontaneous LH pic, HCG

Brief summary

The rational of the study is to assess the implantation, pregnancy and live birth rates after the transfer of frozen- thawed embryos in natural cycles with spontaneous Luteinizing Hormone (LH)/Progesterone rise or in natural cycles controlled by human chorionic gonadotropin (hCG) for final oocyte maturation and ovulation.

Interventions

DRUGHCG

5000IU

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

17 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* age \<40 * BMI:18-29Kg/m2 * day 3 embryo transfers * previously IVF or ICSI

Exclusion criteria

* irregular cycles * oocyte donation cycles

Design outcomes

Primary

Measure	Time frame
Implantation rate	2 years

Secondary

Measure	Time frame
Ongoing pregnancy rate	2 years

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026