Leucine Supplementation in Elderly Men

The Influence of Leucine Supplementation on Body Composition and Muscle Characteristics in Healthy Elderly

Status

Completed

Phases

Phase 1Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00807508

Enrollment

Registered

2008-12-12

Start date

2007-01-31

Completion date

2008-12-31

Last updated

2008-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging, Atrophy, Sarcopenia

Brief summary

In the present study the investigators aim to determine whether leucine supplementation can augment muscle mass and strength and improve body composition in healthy elderly men

Interventions

DIETARY_SUPPLEMENTplacebo

wheat meal capsules with each main meal

DIETARY_SUPPLEMENTleucine

daily leucine capsules with each main meal

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE

Eligibility

Sex/Gender

MALE

Age

65 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* living independently

Exclusion criteria

* Diabetes cardiovascular disease orthopedic limitations history of resistance training in past 5 years

Design outcomes

Primary

Measure	Time frame
muscle mass and body composition	before and after 12 wk intervention

Secondary

Measure	Time frame
muscle strength	before and after 12 wk intervention

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 3, 2026