Evaluation of a Probiotic On Anxiety and Stress in Healthy Adults Sensible to Daily Stress

Evaluation Des Effets Anti-Stress D'un Probiotique Nomme PROBIOSTICK® Sur Des Sujets Humains Volontaires Sains Sensibles Au Stress De La Vie Quotidienne

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00807157

Acronym

BIOSTRESS

Enrollment

Registered

2008-12-11

Start date

2008-12-31

Completion date

2009-04-30

Last updated

2009-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Stress

Keywords

PROBIOSTICK®, Probiotic, Anxiety, Daily stress

Brief summary

The purpose of the the study is to determine if PROBIOSTICK® decrease stress and anxiety of people sensible to daily stress.

Interventions

DIETARY_SUPPLEMENTPROBIOSTICK® during 30 days

Every morning subjects will consume a stick of PROBIOSTICK® during 30 days

DIETARY_SUPPLEMENTPlacebo during 30 days

Every morning subjects will consume a stick of placebo during 30 days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

30 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Caucasian healthy men or women * Age 30-60 years * Hospital anxiety and depression score equal or below 12 and above 4 * Standard safety biology

Exclusion criteria

* HAD A results above 12 and below 4 * HAD D results above 12 * Neurologic or psychiatric pathology * Consumption of psychotropic * High level of caffeine consumption * Any important chronic pathology * Drugs wich impairs concentration, anxiety and stress

Design outcomes

Primary

Measure	Time frame
SCL 90 questionnaire	day 0 and day 30

Secondary

Measure	Time frame
Stress perçu, coping de vitaliano, hospital anxiety and depression questionnaires and urinary cortisol measurement	day-14 ; day 0 and day 30

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026