Comparison of the Effects of Bevacizumab Before vs After Pattern Panretinal Photocoagulation

Phase 4 Comparison of the Effects of Bevacizumab Before vs After Pattern Panretinal Photocoagulation

Status

Terminated

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00804206

Enrollment

Registered

2008-12-08

Start date

2008-07-31

Completion date

2008-07-31

Last updated

2024-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Edema

Keywords

Intravitreal injection of Bevacizumab, Visual acuity, central retinal thickness, color studies, Farnsworth-Munsell, electroretinogram studies

Brief summary

Compare the effect of an intravitreal injection of bevacizumab previous or posterior of panretinal laser photocoagulation (PRLP) with a pattern laser; to prevent and reduce diabetic macular edema (DME) in patients with proliferative diabetic retinopathy (PDR) with DME.

Interventions

DRUGbevacizumab

Intravitreal bevacizumab before panretinal photocoagulation

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients with proliferative diabetic retinopathy * patients with macular edema

Exclusion criteria

* patients with previous treatments * patients with ocular surgeries

Design outcomes

Primary

Measure	Time frame
Central macular thickness	baseline, 10 days, 52 days, 85 days

Secondary

Measure	Time frame
Best corrected visual acuity	baseline, 10 days, 52 days, 85 days

Countries

Mexico

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026