Serum Citrate in Diagnosis and Follow-up for Glaucoma

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00804063

Enrollment

Registered

2008-12-08

Start date

2008-12-31

Completion date

2013-07-31

Last updated

2015-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Keywords

glaucoma, citrate

Brief summary

Glaucoma might be a mitochondria associated disease. Since citrate is a major component in mitochondrial metabolism its determination in blood might serve as a biomarker.

Interventions

PROCEDUREdrawing blood sample

fasting blood sample

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* age\> 18 years * glaucoma

Exclusion criteria

* Active ocular inflammation * Ocular Hypertension * Nephropathy * Alcohol-, Drug abuse * Mitochondriopathy

Design outcomes

Primary

Measure	Time frame
serum citrate level	1

Secondary

Measure	Time frame
urine citrate	1

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026