Cataract
Conditions
Keywords
cataract, phacoemulsification, irrigation solution, endothelial cell density, corneal thickness
Brief summary
Two intraocular irrigating solutions (BSSPlus versus Lactated Ringer's) are compared in this prospective, randomized, masked trial to investigate for differences in preservation of corneal integrity after phacoemulsification cataract surgery.
Interventions
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with senile cataract * Visual acuity between 20/400 and 20/40
Exclusion criteria
* Presence of corneal opacity * Presence of corneal disease * Traumatic, toxic, hereditary (congenital)and complicated cataracts(uveitis) * Anterior chamber cells or flare detected before surgery * Previous ocular surgery * Any condition which may affect documentation or follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endothelial cell density | baseline and at 1, 8, 15, 30 and 60 days postoperatively |
| central corneal thickness | baseline and at 1, 8, 15, 30 and 60 days postoperatively |
Secondary
| Measure | Time frame |
|---|---|
| number of anterior chamber cells and flare grade | baseline and at 1, 8, 15, 30 and 60 days postoperatively |
Countries
Brazil
Outcome results
None listed