Scleral Thinning
Conditions
Keywords
Amniotic membrane, Cornea, Scleral thinning
Brief summary
The purpose of this study is to evaluate the use of preserved scleral, corneal and amniotic membrane graft for the surgical repair of scleral thinning of different sizes in patients underwent surgery of pterygium with associated beta therapy .
Detailed description
Scleral thinning may occur secondary to different ocular surface conditions, especially in rheumatologic diseases and after surgeries as in pterygium. There are different methods to treat this condition, as to use scleral, corneal and more recently amniotic membrane graft.
Interventions
PROCEDUREHuman Amniotic Membrane Transplantation
Human Amniotic Membrane Transplantation for The Treatment of Ocular Surface Disease
Sponsors
Federal University of São Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients with corneal scleral defects that have persisted for 1 years or longer, regardless of their cause. These patients will have received corneal-scleral or amniotic membrane transplant in order to correct scleral thinning * Patients with history of pterygium surgery associated with beta therapy followed by scleral thinning
Exclusion criteria
* Ocular infection * Acute ocular inflammatory condition * Previous ocular surgery in the eye study * Non-controlled systemic disease such as rheumatoid arthritis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The surgical procedure was randomized in scleral, corneal or amniotic membrane graft. Nine patients underwent surgery with scleral graft that was covered by conjunctival flap; ten with corneal graft and ten with amniotic membrane transplantation. | Patients were followed for 180 days. |
Outcome results
None listed