The Effects of Potassium on Physiological and Cardiovascular Variables in Healthy Persons

The Effects of Potassium on Physiological Variables in the Kidney and Cardiovascular Variables in Healthy Persons in a Double-blinded, Randomised, Placebo-controlled, Cross-over Study

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00801034

Enrollment

Registered

2008-12-03

Start date

2008-11-30

Completion date

2011-11-30

Last updated

2015-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Keywords

hypertension, potassium, blood pressure

Brief summary

In humans living of fruit and vegetables, hypertension is rarely seen. We wish to study if the development of hypertension has a connection to our intake of potassium. We know that fruit and vegetables contain a lot of potassium and we will simulate this intake by giving healthy subjects potassium as tablets.

Interventions

DRUGCalcium

tablets, 1 tablet 2 times per day in 28 days

DRUGPotassium

Tablets, 5 tablets 2 times per day for 28 days

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy * age 18-40 years old * BMI 18, 5-30 * non-smoker

Exclusion criteria

* daily use of medicine * alcohol or drugs * desire to become pregnant * not using safe anti-contraceptive * abnormal results in the initial testing

Design outcomes

Primary

Measure	Time frame
Effect on blood pressure	three months

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026