IVF Clinical Trial of Two Different Treatment Protocols.

Efficiency and Patient Satisfaction of Two Different IVF Protocols.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00799929

Enrollment

564

Registered

2008-12-01

Start date

2008-12-31

Completion date

2014-10-31

Last updated

2015-12-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Keywords

IVF Research Study, Infertility Sudy, in vitro fertilization, Mini IVF, Conventional IVF

Brief summary

The purpose of this study is to compare two different in vitro fertilization (IVF) treatments: conventional IVF protocol and minimal stimulation IVF protocol, in terms of success rates, stress of treatment, drug-related side effects, multiple pregnancies and cost of treatment.

Detailed description

A random population of 564 sub-fertile women or couples with a female between ages of 18 and 38 years and a desire to undergo their first IVF cycle will be included in this outpatient clinical trial. The participation in this study will be approximately six months with a total of 20 to 25 visits. After successful completion of the pre-screening tests participants are randomized into one of the two arms of the study: Arm A - mini IVF protocol, and Arm B - conventional IVF protocol.

Interventions

OTHERin vitro fertilization (IVF/ICSI)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 38 Years

Healthy volunteers

Inclusion criteria

* Valid indication for IVF treatment * First IVF attempt * Female age between 18 and 38 years * Male partner 18 years of age or older * Both partners STD free * Must be able to understand that they may NOT become pregnant

Exclusion criteria

* Not willing or able to sign the consent form * Pre-existing medical condition preventing/interfering with IVF treatment * Abnormal IVF screening tests, which includes Complete Blood Count, Varicella titer, Rubella titer, PAP smear, Syphilis, HIV 1&2, Hepatitis B, Hepatitis C, Chlamydia, and Gonorrhea * Abnormal pap smear * Body Mass Index (BMI) falls below 18.5 or above 32.0 * Female participant with irregular menstrual cycles

Design outcomes

Primary

Measure	Time frame
Primary outcome parameter: Live birth	4 Years

Secondary

Measure	Time frame
Secondary outcome parameters: Biochemical pregnancy, Clinical pregnancy, Ongoing pregnancy, Multiple pregnancy rate, Miscarriage rate, Fertilization rate, Number of oocytes, Number of embryos	4 Years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026