Empyema, Pneumonia
Conditions
Keywords
Empyema, Urokinase, Thoracoscopic, Childhood
Brief summary
A great controversy exists about which is the best method to perform the evacuation of the collection. The purpose of this study is to evaluate which is the best initial treatment to drain complicated parapneumonic empyema (stages II and III) in children: the present study raises a hypothesis of equivalence between both arms of treatment (chest drainage plus intrapleural urokinase or videothoracoscopic debridement).
Interventions
DRUGUrokinase
Chest tube with intrapleural urokinase infusion for 3 days
PROCEDUREVideo-Assisted Thoracoscopic
Video-Assisted Thoracoscopic decortication
Sponsors
Spanish Society of Pediatric Surgery
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Years to 15 Years
Healthy volunteers
No
Inclusion criteria
* Patients less than 15 years of age with pneumonia and persistent fever, and complicated parapneumonic empyema (septation or loculation seen on ultrasound or Rx thorax)stages II and III requiring an intervention to drain
Exclusion criteria
* Existing contraindications or other previous conditions, hypertension, pneumothorax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| duration of the hospital stay after the treatment | 3 months |
Secondary
| Measure | Time frame |
|---|---|
| complications of the treatment and complications of the disease | 3 months |
| total duration of the hospital stay | 3 months |
| number of days carrying the chest drain | 3 months |
| duration of the fever once the empyema has been drained | 3 months |
Countries
Spain
Outcome results
None listed