Convulsive Diseases
Conditions
Brief summary
The purpose of this study is to evaluate the efficacy of Xingnaojing for the treatment of convulsive diseases; to investigate whether convulsion episodes can be induced or aggravated by Xingnaojing and the role inflammation plays in the process.
Interventions
DRUGXingnaojing
injection
Sponsors
Shenzhen Children's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Months to 18 Years
Healthy volunteers
No
Inclusion criteria
1. Febrile convulsion: positive family history of febrile convulsion; aged between 6 months and 6 years old; in accordance with the diagnosis criteria of simple type of febrile convulsion 2. Frequent episodes of epilepsy: epilepsy episodes of all types; \> 3 times / week 3. Refractory epilepsy: no satisfactory efficacy after treatment by 2\ 3 antiepileptic drugs; ≥ 1 time / month 4. Cerebral palsy: all types of cerebral palsy in children less than 3 years old. -
Exclusion criteria
1. Febrile convulsion: family history of epilepsy, complex type of febrile convulsion, epileptic episodes, febrile convulsion plus 2. Frequent episodes of epilepsy: combined with advanced diseases 3. Refractory epilepsy: epilepsy combined with advanced diseases 4. Cerebral palsy: advanced diseases combined with backwardness or retardation of brain function development.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antipyretic rate , Frequency of convulsive episodes , | one year |
| Frequency of convulsive episodes | 1 year |
Outcome results
None listed