Reproducibility of Magnetic Resonance Myocardial Salvage Index

Reproducibility of Myocardial Salvage Index in Acute Myocardial Infarction by Cardiac Magnetic Resonance Imaging

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00794300

Enrollment

250

Registered

2008-11-20

Start date

2008-11-01

Completion date

2010-05-01

Last updated

2018-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial Infarction

Keywords

reproducibility, contrast agent, magnetic resonance imaging, infarct size, myocardial salvage index, myocardial salvage assessment

Brief summary

The myocardial salvage assessed by using multimodal cardiac magnetic resonance imaging is a rather new technique which can be used as a surrogate endpoint to reduce the sample size in studies comparing different reperfusion strategies in myocardial infarction. As reproducibility of myocardial salvage has not been evaluated appropriately, we aim to scan 20 patients on 2 subsequent days to evaluate reproducibility of myocardial salvage index.

Interventions

DEVICEsecond magnetic resonance imaging scan

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* ST-elevation myocardial infarction * Primary percutaneous coronary intervention

Exclusion criteria

* Contraindications for magnetic resonance imaging

Design outcomes

Primary

Measure	Time frame
Myocardial salvage index reproducibility	2 days

Secondary

Measure	Time frame
infarct size reproducibility	2 days
area at risk reproducibility	2 days
microvascular obstruction reproducibility	2 days

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026