Edema, Pain, Trismus
Conditions
Keywords
trismus, Edema, pain
Brief summary
The purpose of this study is to determine whether Etodalac, Etoricoxib and Dexamethasone are effective for Prevention of Pain ,Swelling and Trismus Following Third Molar Surgery
Interventions
DRUGEtodalac, Etoricoxib and Dexamethasone
Dexamethasone sodium phosphate 8 mg 1 hour before the extraction, 4 mg the day after the extraction and another 4 mg at second day to the extraction. Etoricoxib 120 mg 1 hour before the extraction, 120 mg the day after the extraction and another 120 mg at second day to the extraction. Etodalac 600 mg 1 hour before the extraction, 600 mg the day after the extraction and another 600 mg at second day to the extraction.
Sponsors
Tel-Aviv Sourasky Medical Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients who are refered for third molar extraction to our center * Must be able to swallow tablets
Exclusion criteria
* Diabetes mellitus * Thyroid diseases * Cardiovascular diseases * renal diseases * hepatic diseases * respiratory system diseases * adrenal diseases * Allergy to Etodalac, Etoricoxib or Dexamethasone * Gastric ulcers * psychiatric diseases * Pregnant or breast feeding womans
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PAIN- By VAS graded from 1-10 TRISMUS- By MAX mouth opening from the first incisors adages POST OPERATIVE SWELLing - By measurement the distance between the Right and LEFT ear's tragus | 1 week |
Outcome results
None listed