Pain
Conditions
Keywords
Tsui test, Epidural Analgesia
Brief summary
Low current electrical stimulation test, also called the Tsui test, has been used successfully to confirm the catheter location in the epidural space in various patient populations. The results of this study will show whether or not doing a Tsui test can predict inadequate epidural analgesia early in the course of placing the epidural, so that the appropriate measures could be applied immediately upon gathering unfavorable results.
Detailed description
Despite its very high success rate, the epidural technique remains a rather blind technique, and failures continue to occur. The incidence and reasons for failure are not well understood. The Tsui test is not routinely performed with each epidural catheter insertion, but rather it is used when there is suspicion about the catheter location. In this study, the Tsui test will be performed twice during the epidural procedure, and bupivacaine consumption will be recorded for the first 2 hours. Information gained from this study could have great impact in clinical practice, since the incidence of inadequate labor analgesia is still relatively high (10-20%), leading to maternal distress and disappointing labor experience.
Interventions
PROCEDURETsui test
The stimulator is set at frequency of 1Hz with 200ms pulse width and the current output ranging from 0 to 20 mA. The current output will be carefully increased from zero until motor activity is detected up to a maximum of 20 mA.
Sponsors
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Women over 18 years of age requesting an epidural for labor and delivery * Cervix dilated 0-5 cm and pain VAS\>6 * Able to communicate in English * Informed consent
Exclusion criteria
* Refusal to provide written informed consent * Patients unable to communicate in English * Contraindication to regional anesthesia * Allergy or hypersensitivity to lidocaine, bupivacaine or fentanyl * Sedatives or opioids received prior to insertion of epidural catheter * Abnormal vertebral anatomy, such as previous spine surgery and scoliosis * Coexisting neurological disorders * Patients with implanted electronic devices
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consumption of bupivacaine in mg/hour in the first 2 hours of epidural anesthesia | 2 hours |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of inadequate epidural block. | 2 hours |
| Current (mA) needed to elicit motor response; 1. before test dose and 2. 5 minutes after test dose. | 5 minutes |
| Contraction pattern elicited by the Tsui test at baseline and after test dose. | 5 minutes |
Countries
Canada
Outcome results
None listed