Loaded Breathing Training in Essential Hypertension

Effects of Loaded Breathing Training on Blood Pressure in Essential Hypertensive Patients

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00791986

Enrollment

Registered

2008-11-17

Start date

2006-05-31

Completion date

2008-12-31

Last updated

2018-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential Hypertension

Keywords

Breathing exercise, blood pressure, hypertension

Brief summary

The purpose of this study is to determine whether adding load to slow controlled breathing training could enhance blood pressure lowering in patients with essential hypertension.

Detailed description

Hypertension (HT) is one of the major risk of cardiovascular diseases and cost of pharmacological treatment is a very high. Lifestyle modification is the first trial in stage 1 hypertension before commencing pharmacological treatment and a co-treatment with drug in hypertensive patient. Slow paced breathing training and physical training has been shown to reduce both systolic and diastolic blood pressure in HT. Moreover loaded breathing was reported to be able to decrease blood pressure in healthy. Loaded slow breathing training may enhance the antihypertensive effect of slow paced breathing.

Interventions

DEVICEULB , LB

ULB: The patients breath in slowly without resistance via the water pressure threshold breathing (WPTB) device, 30 min/day, 7 days/week for 8 weeks. LB : The patients breath in slowly against resistance of 20 cmH2O provided by the water pressure threshold breathing (WPTB) device, 30 min/day, 7 days/week for 8 weeks.

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

35 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of essential hypertension stage I-II

Exclusion criteria

* Respiratory disease * Diabetes mellitus * Heart disease * Renal disease * Cerebrovascular disease * Dyslipidemia * Pregnancy

Design outcomes

Primary

Measure	Time frame
Home blood pressure	Pre- and post - 8 weeks of intervention at rest

Secondary

Measure	Time frame
Heart rate variability	Heart rate variability at pre-and post- 8 weeks of intervention
Office blood pressure	Pre- and post- 8 weeks of intervention at rest
Exercising blood pressure	Blood pressure during exercise at pre- and post-8 weeks of intervention

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026