Mechanisms of Fronto-Subcortical Dysfunction: Comparing PD and OCD

Characterizing Mechanisms of Fronto-Subcortical Dysfunction: A Comparison Between Parkinson's Disease and Obsessive-Compulsive Disorder

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00790634

Enrollment

100

Registered

2008-11-13

Start date

2008-12-31

Completion date

2011-12-31

Last updated

2008-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-Compulsive Disorder, Parkinson's Disease

Brief summary

The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

16 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* idiopathic PD or * OCD * for control group - age-matched to study groups

Exclusion criteria

* psychotic symptoms (past or present) * head injury with loss of consciousness * other neurological conditions (excepting PD in PD group) * for OCD group - use of dopaminergic medications

Contacts

Primary ContactSharon Hassin, MD

shassin@post.tau.ac.il97235305791

Backup ContactSari Meril, M.Sc

972

Outcome results