Penicillin Skin Testing in Patients With History of Allergic Reactions to Betalactams

The Comparative Results of Penicillin Testing in Patients With History of Allergic Reactions to Betalactams Between Using In-house Penicillin Test Preparation and Commercial Available Penicillin Testing Kit

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00789217

Enrollment

Registered

2008-11-11

Start date

2008-12-31

Completion date

2010-08-31

Last updated

2010-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Penicillin Allergy

Keywords

Penicillin, Beta-Lactams, Allergy, Hypersensitivity

Brief summary

This study aims to compare the readings of skin testing results in patients with suspected penicillin allergy between in-house penicillin test preparation and commercial available penicillin testing kit.

Detailed description

The results of skin test with immediate reading will be compared between alkali-treated penicillin G and DAP reagents from Diater

Interventions

PROCEDUREImmediate skin test

Intradermal test with immediate reading

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

15 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients with history of hypersensitivity reactions to betalactams; penicillin, aminopenicillins, and cephalosporins 2. 15-65 years of age

Exclusion criteria

1. On antihistamine/ cannot discontinue antihistamine before the test 2. Having asthma exacerbation 3. Being pregnant 4. Suffering from severe systemic disease/ in bad health

Design outcomes

Primary

Measure	Time frame
The skin testing results of in-house penicillin skin test and Penicillin G Sodium compared to commercial penicillin testing kit	1 year

Secondary

Measure	Time frame
Clinical correlation and side effects	1 year
Correlations between Penicillin skin test result with specific IgE and/or basophil activation test	1 year

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026